DPCstruct | MC48412

Metacluster Properties and Pfam Annotations

Number of structural domains1641
Mean domain length (aa)204 ± 46 aa
Standard deviation of domain lengths46.01
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score85.41
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)15.53
Pfam Score69.34
Assigned Pfam label(s) PF01556- CL0080- CL0144- CL0177- CL0200

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I1T8W8 7-202 YTPRTSATRVHWVLEELGVRYEKVKVDLRAGEQHKPEFLAINPNGKVPALVVDGTPMFESLAIILYLGDRFGVDKGLWPRVGTGEHA…
F4NFN6 7-192 ACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTI…
A0A7M3RK10 288-515 None
A0A7M3RZH8 16-176 None
S9S9F1 155-355 None
A0A6A5UZN8 9-230 None
A0A1V8T212 5-256 None
A0A1V8SHD4 388-581 None
I3LZX6 6-220 None
A0A1D2MZF2 9-285 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.