DPCstruct | MC48396

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)141 ± 24 aa
Standard deviation of domain lengths24.45
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score71.18
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)25.47
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A178AHA9 46-192 GDELGLEISVDLLAALTGAQHVVDYRDSAMMKGYSHLFVPVKKRPESVQWHMIVSPDAGRWVKYEDSATLIASGGSIAKVSIAEATS…
A0A2J6R1I4 87-202 GSCWRPLFRNPVIVEGYPILARAHGEKGLEIPLDMMAGLSQASRVTNFGGGLVIKGFSTMFCPTKRIKNSVLWHYLFSHDGKRMSYL…
A0A0L1JIZ9 278-417 None
R1EC65 158-312 None
A0A6A5SCG2 53-218 None
A0A2P4ZP35 176-312 None
A0A5N6WBV5 9-148 None
G3JD53 543-649 None
A0A146FNX1 388-506 None
A0A5N6ED00 230-374 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.