DPCstruct | MC48360

Metacluster Properties and Pfam Annotations

Number of structural domains493
Mean domain length (aa)198 ± 42 aa
Standard deviation of domain lengths42.45
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score75.96
Mean fraction of residues predicted as intrinsically disordered0.58
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)20.44
Pfam Score97.91
Assigned Pfam label(s) CL0114- CL0123- CL0012- CL0003- PF12554

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A545VHE9 1-197 None
A0A168KXY8 152-371 None
A0A162QDP3 177-371 None
A0A813TN57 68-278 None
A0A437DLP0 591-966 None
A0A7I8VQL3 92-243 None
A0A182VUC4 132-268 None
A0A4S4DQQ6 21-276 None
A0A1Y2GFA2 4-221 None
H3CHG8 1-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.