DPCstruct | MC48312

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)302 ± 26 aa
Standard deviation of domain lengths25.61
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score76.57
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)26.09
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E7N708 77-376 LPHRLESGERSFAFYRGPLTATPAQALPAPADPRLESAGEALVYLRAHGVFDTGYASAFSLGRTLALADAPFRGKLLEFRKAARRAV…
A0A6M5FZF2 2-305 IYDAQSAVFDLSLACAWEAGRLSAVSDQVYVRQILALRKKAQQIADVLFSRMLSRAAESGKKDTLDRPEEFAQSARKELEQLGKEEW…
A0A0B4GV34 319-657 None
A0A2T5LKV6 370-657 None
A0A2L2TUM2 90-353 None
A0A5B2VM80 356-647 None
A0A0F4GR08 482-788 None
W9NNH6 418-715 None
A0A4Q2VGX5 212-509 None
A0A1V5F5H8 167-514 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.