DPCstruct | MC48303

Metacluster Properties and Pfam Annotations

Number of structural domains274
Mean domain length (aa)115 ± 28 aa
Standard deviation of domain lengths28.06
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score82.50
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)16.23
Pfam Score98.76
Assigned Pfam label(s) CL0441- CL0020- PF07426

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A813NA27 20-141 VSLSLPYALHASCLHMQVRSGSKTKNLVQFAMRKLFPTDQNAINVEQITWNAFGDGISKAIACAELTKRRSQLNFYEYVQIGYKRIE…
A0A3S0ICJ1 1-83 MMQLKVASNSAPKALAGAVSGLLRAEPQVELLAVGPHAVNQAVKALAIARGYLEADGIDVIVQPAFAPAAQGGVQLVLLATAI
A0A835J2W4 120-197 None
S7RN20 3-185 None
A0A843X233 1-122 None
A0A447G300 170-270 None
A0A1X2IMC1 151-298 None
A0A7S0A4M2 84-193 None
A0A7C9DIL5 2-69 None
U2Z819 375-468 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.