DPCstruct | MC48280

Metacluster Properties and Pfam Annotations

Number of structural domains123
Mean domain length (aa)260 ± 55 aa
Standard deviation of domain lengths54.98
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score71.23
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)15.11
Pfam Score41.95
Assigned Pfam label(s) PF08577- CL0271- PF11566

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A194RGH2 11-253 ENISSLLDTLSREVLSQNKGTEPVQNDLFYVLIIVLMLENGFLPVINDSEVMENINSYDVQHLIPKKLETGLYEAKFVMFGCPDFPL…
A0A1Y1KBW4 20-220 NVFTYCIKSGICVDKNDTMAIFIYIMMLEAGFVTPDYSNPQEESTCNVHSSFHYQRFLHLTRALPKNWKQNNVYNFTFILAPFTQHQ…
A0A817Q7N0 141-422 None
A0A835XW56 282-568 None
A0A097H178 7-182 None
A0A819PDE0 96-341 None
A0A061R0Z6 8-198 None
A0A653C2A6 14-260 None
A0A0G4HG89 2-299 None
J6F3K8 88-482 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.