DPCstruct | MC48199

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)486 ± 55 aa
Standard deviation of domain lengths55.06
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score71.57
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)32.44
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A372QE77 28-493 VSRLHLCYTQGINIINLFYMENGLKITTKKFDELKQIYLLEFIDSDKKLFIIGECLKGNIVSIIWDIYNTAKRKQIELDNFPINKFK…
A0A2P4PZ89 174-660 LLSRSIENDYFLIEDYKDRVQVVEMYNLRTDKLEMVFHQRAESAVTAFGHGNPAVAISKHNALLAYCRGANSITIYLIENSLEISTQ…
A0A2I1ES84 1-393 None
A0A2I1FAK3 20-542 None
A0A2Z6RAK9 4-544 None
A0A2N1N988 1-487 None
A0A015N1U4 2-501 None
A0A2N0S363 406-888 None
A0A015KRX6 27-551 None
U9SSB2 3-461 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.