DPCstruct | MC48111

Metacluster Properties and Pfam Annotations

Number of structural domains92
Mean domain length (aa)133 ± 17 aa
Standard deviation of domain lengths17.33
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.74
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)29.73
Pfam Score99.31
Assigned Pfam label(s) CL0010- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1H0B0 11-129 FDIITKRKIHCTVCRGHLGCAPGKEDNIKMHPVLRVMQCSDCHEFYSSGEFSRGEDGSELYCRWCGQGGQVYCCSSCPYVFCKSCIV…
B0X8C4 86-213 PNVNKIAERKVHCTSCYMHIGTAPISEAVIRMHPVLRVTHCRNCHTFYNSGEFDKGEDGSELYCRWCGQGGEVYCCSKCPYVFCKKC…
A0A7E5X444 45-182 None
A0A2Y9QA88 5-131 None
A0A6I8T2T0 234-367 None
A0A6P8HD78 156-279 None
A0A834XMX8 400-545 None
A0A182FVT4 34-152 None
A0A1I8IPI0 72-215 None
A0A1I8IHU3 71-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.