DPCstruct | MC48015

Metacluster Properties and Pfam Annotations

Number of structural domains3315
Mean domain length (aa)201 ± 42 aa
Standard deviation of domain lengths41.69
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.32
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.26
Pfam Score94.03
Assigned Pfam label(s) CL0550- PF02135- CL0110- PF07735- CL0389

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y9ZSA9 2-250 None
A0A448ZMI7 4-177 None
E3M7B2 226-413 None
E3MJ27 131-308 None
E3MNV7 135-290 None
E3MPI0 49-157 None
E3MQK0 114-222 None
E3MTA6 111-299 None
E3MTA3 551-678 None
E3MTP1 576-755 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.