DPCstruct | MC47990

Metacluster Properties and Pfam Annotations

Number of structural domains277
Mean domain length (aa)85 ± 13 aa
Standard deviation of domain lengths12.54
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.17
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)21.70
Pfam Score83.55
Assigned Pfam label(s) CL0023- PF00571- CL0428- PF04972- CL0232

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4R5A9J1 123-205 None
A0A2E3FB94 1-101 None
A0A7V6YZG8 106-200 None
A0A7V7VJW8 7-105 None
A0A535ITD7 166-245 None
A0A1Y0D8H6 67-177 None
A0A5C6AGD0 24-111 None
A0A399IW98 264-339 None
A0A832C895 121-202 None
A0A5C7S7C0 67-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.