DPCstruct | MC47990

Metacluster Properties and Pfam Annotations

Number of structural domains277
Mean domain length (aa)85 ± 13 aa
Standard deviation of domain lengths12.54
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.17
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)21.70
Pfam Score83.55
Assigned Pfam label(s) CL0023- PF00571- CL0428- PF04972- CL0232

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A085ZEE5 15-87 EQVIKAEKAFFISQDISEKIIDTFNVCNLRVSATADGTVSISGIVDNDNEKRDIQNFVLQLESVSSCYNGLEI
Q2L114 21-106 LAHAAEAQPKQSVGEYASDAAITAKVKAAIVADKDLSALDIAVETNNGVVTLTGTVGTAFQADRAAIVTRGVDGVKQVKNDVKVEM
A0A829XWR2 71-157 None
A0A1G6RDL4 2-106 None
A0A1V1V479 14-95 None
W6W3Q6 10-88 None
A0A7C3MSY5 346-425 None
H2FX49 39-137 None
A0A535A1H4 91-167 None
A0A840I365 1-118 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.