DPCstruct | MC47848

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)101 ± 23 aa
Standard deviation of domain lengths22.67
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score93.53
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)46.88
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q5X2M6 244-335 GNVSVESYVELHDPDHKVKFALVNEFTTDRVLTGADFDVESMRVAPDGTIWIGDELGPFLLHFDSAGKLLDEPLALPDPENPAREVR…
A0A0Q9J445 139-225 GEIEIERFITYNDADRVLDFPIVNEATPDRLLTGADFDIESVVLAKDGTFWVGEEFGPFLLHFDSDGTLLEKPYPLPGGAKSPQNPY
A7BMN1 26-151 None
H8GTD2 88-166 None
A0A6V8KY11 1-115 None
A0A7J6ZF80 205-331 None
A0A6L9YC84 97-174 None
A0A2N4T0A9 17-134 None
Q8Z028 96-163 None
A0A1W9JC16 45-179 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.