DPCstruct | MC47839

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)177 ± 28 aa
Standard deviation of domain lengths28.13
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score91.62
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)47.32
Pfam Score100.00
Assigned Pfam label(s) CL0088

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377E329 15-223 HEMSSGKDTPSGHWEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVF…
B4D6X8 29-226 AGKDSTTGHWEMAGAILDHPFATFTEFPADFVAAISRDAKVEFLGNYARSGTTILEELGSEHLRTGKPILYTSADSVLQIAAHEQVI…
A0A376K6M5 17-146 None
A0A7E4RZW9 736-910 None
A0A3D2CNY1 94-264 None
A0A4Q3VBM5 172-329 None
A0A3S4NEJ6 1-156 None
A0A2X3F2U5 85-300 None
A0A3D9KUY9 398-595 None
A0A077ZFN7 1071-1247 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.