DPCstruct | MC47837

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)139 ± 8 aa
Standard deviation of domain lengths8.46
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score83.19
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)29.43
Pfam Score100.00
Assigned Pfam label(s) CL0373

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377E1E1 1-148 MMPFSNVEAWINSELATEFAEQEEIAFTSGDGTKKPKGFLAYESTDETDKVRAFGKLQHIVSGEATAVTADAIIKLIYTLRKAHRTG…
A0A223I0W6 211-346 SVFNLEQYIAKEFARRIGAKEEEAFFIGDGSGKPTGILADNGGGEIGVTAASATAITLDEIMDLFYSLKSPYRRNAVFIMNDSTIKA…
A0A1V2H8J5 28-169 None
A0A386UM55 57-208 None
A0A4R4A8U2 254-382 None
A0A560FKK8 632-763 None
A0A2R4JY38 67-214 None
A0A7V4ZD68 542-674 None
A0A524INM6 333-457 None
A0A7Z8LRS0 106-251 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.