DPCstruct | MC47777

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)142 ± 11 aa
Standard deviation of domain lengths10.96
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score83.78
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)50.12
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0D3C5A1 24-170 MNGMLGHLERQPKNKERCMAWLRFVEPLLKALGRFLLAHFRRIFPLFFQWTHSDDPETVLLVLERVETVLRLTWIGNSPRFNPKHYK…
A0A287XIX7 69-213 MLGHLERQPLNKERRVAWLTLIGPVLDAMGLFLLAHFRLLFSLFFQWMHADDDRTVLLVLERIHTVVKLTWIRKSPYTSRLVDELVL…
A0A2R6RRA6 2-146 None
A0A835UKX5 1-147 None
A0A453SR98 1-147 None
A0A7N0TPJ4 99-240 None
W9RJ34 288-433 None
A0A7S2QZ02 3-125 None
A0A446YRW6 57-169 None
D8SM01 256-401 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.