DPCstruct | MC4777

Metacluster Properties and Pfam Annotations

Number of structural domains136
Mean domain length (aa)211 ± 51 aa
Standard deviation of domain lengths50.63
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.15
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.22
Pfam Score97.50
Assigned Pfam label(s) CL0490- CL0320- CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q9BGB9 8-187 SRWLHIYLSMFSFIIVLFFSVTGLTLNHVDWFPESTVVSELKGSVNASWVSVADTAKIPKLDIVEQLRANHSIKGQLNDFRIDEEEI…
A0A846H4M9 62-270 CILTITGLVLWPGWRKLIAGFKIKLDAHPQRANFDIHKVAGIITVVFLFFTGFTGFCWNFYDLTEPIIYAVTFTPKPSELVSKPIPG…
A0A2S6HFD1 8-193 None
A0A2E9AU47 4-173 None
A0A1B3X686 41-365 None
A0A258R345 4-175 None
A0A418VUK8 175-378 None
A0A0H2MCI5 97-332 None
A0A6G7BNX2 170-429 None
A0A1C9VEY9 116-432 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.