DPCstruct | MC4774

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)107 ± 8 aa
Standard deviation of domain lengths8.16
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score89.96
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)32.25
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C6TGC9 147-246 TAKAKRERREAFESHLRAFRARFQDAEYPPEAEVEGETVYDTYSIYGTGSRIVIGDTWVWWVDNNGMDGDDWSRNNCRLGIARRLPR…
A0A077MBD9 6-99 HRVRKMEARAIARTIETDGERPERAGYPDGDHFLGERTLYGGGQWVVVDADYIWSMHGNGADGDDWSANNVGGNIGWRIPRTDKMVA…
A0A842RM10 95-207 None
A0A7C6H8S7 182-286 None
A0A1G3M7G0 342-448 None
A0A2J6WX59 170-281 None
A0A259N713 242-344 None
A0A843F3J8 17-138 None
A0A2P1PZL4 326-427 None
A0A246BTG8 143-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.