DPCstruct | MC47675

Metacluster Properties and Pfam Annotations

Number of structural domains285
Mean domain length (aa)176 ± 33 aa
Standard deviation of domain lengths33.47
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.78
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.84
Pfam Score99.23
Assigned Pfam label(s) CL0237- CL0318

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5D0IKU5 2-163 LEKTKDYAIKKHKDVNQKYGDYDYDFHLNMVYETAQKFIHIIAPEERENVLAACWVHDVIEDARETYNDVKNVTNTTIAELAYALTN…
A0A0L0LHN8 6-178 SSLLDRATRMAVDGHAIQVRKDDNSPYIVHPVMVAILLAQHGFSETVIAAGLTHDLVEDTEYTIDQIREELGDEVATIVASVTNQEG…
A0A4V0X3X3 20-207 None
A0A1V5IL88 40-231 None
A0A1H6EQW4 24-191 None
A0A2Z4FIE0 5-186 None
A0A261DD08 1-165 None
A0A6C1NUW7 9-154 None
A0A7G7HWC8 3-142 None
A0A1Q6K549 3-152 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.