DPCstruct | MC47584

Metacluster Properties and Pfam Annotations

Number of structural domains73
Mean domain length (aa)178 ± 33 aa
Standard deviation of domain lengths33.07
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score75.83
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)20.29
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A4GZW5 1-188 MSRDTTTPTDKTYTIGESFYPIAPCEFERYERSDVVPDIQFPFDIQPGTVSFTHEPPKKGWVRYMHPEGAQYFCLQHALFMVYTDAN…
X8J893 2-167 IIHPEGLPYFHQDKLVTSDNLDDPHVKELVASAVALVCCMLRHMKDIQEDFKFHDEVELCVELKSTDYPPKFNYYIADHAKQTIFWA…
A0A166HBT8 2-171 None
A0A5K1K4V5 44-229 None
A0A165Y806 56-282 None
A0A0D2P0W8 5-108 None
A0A2H3D5Z6 95-273 None
A0A2H3CZL1 1-169 None
A0A1J8QNY3 175-346 None
A0A369JDE7 24-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.