DPCstruct | MC47499

Metacluster Properties and Pfam Annotations

Number of structural domains713
Mean domain length (aa)146 ± 30 aa
Standard deviation of domain lengths29.74
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score89.96
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.72
Pfam Score98.28
Assigned Pfam label(s) CL0170- PF18979- CL0020- CL0244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C7ACF4 133-288 SIIVDLRYASNNNFMGFQIYPDNSRAYLRRETAVKLLQASEIFKKDGYYIKIWDAYRPLSAQKIMWEHSPLPGYIANPDNGSKHNRG…
A0A6I2FP22 2-104 LAAAYSHAADAAREEGVTIWITSGYRTPAEQQAMWEDGIRKYGSPEAARQWVLPPEDSTHVSGKAIDVGPRAGAQWLEDNGNRWGLC…
A0A848UEX7 26-147 None
A0A351CPF3 6-149 None
W4CH36 2-112 None
A0A2V7Y550 202-345 None
A0A7Y4ZGZ9 80-251 None
A0A7Y4ZH05 188-376 None
A0A7Y4ZJY7 7-106 None
A0A356K3G6 294-435 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.