DPCstruct | MC47350

Metacluster Properties and Pfam Annotations

Number of structural domains117
Mean domain length (aa)153 ± 26 aa
Standard deviation of domain lengths26.30
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.34
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)22.05
Pfam Score80.99
Assigned Pfam label(s) CL0290- PF18052- PF05189

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0V1AF73 19-153 SNIKPMNLDDDTYRPSLSQGLGIMAIAEYTSGCLIAVDRIVEDEENSDELVKMINDDMKAVLDLPTCVDPHLQDQLIILMALASGVS…
A0A3A0A0Y5 275-428 TIPARGEFRQLQIASYASRELRERQVASRQASACQNRLGLRPAAVDMAHVETFSPGSVITAVAEYEQTRLGADALGERGKPSERVGR…
A0A1Y6LJA1 199-394 None
A0A7V0VZZ5 19-157 None
A0A2U1S0C3 195-349 None
A0A401L0J9 217-405 None
A0A815JWK5 214-384 None
A0A6A5Y3F7 240-416 None
A0A497I391 139-271 None
A0A848A3U4 60-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.