DPCstruct | MC47292

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)113 ± 24 aa
Standard deviation of domain lengths23.52
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score83.61
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)35.49
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D0MXC2 4-108 RYKPELVKFMSYKDNVSYSKDHTFTTEALLRITPEDLCRWMNRQTYGDSEPSDEMRPIHRRLTTLEFTKKAISSFTPRINSAWDPLT…
K0RVC9 62-182 MPRNKKYEPRLRELMQYVHRCEEPYEKGTTFTREQLLELKPEHIEGWLKMKAYGTDCPDIENGDRPIHARSSSLENSKKSVSFFMPN…
W2LP96 1-116 None
W2LXU8 3-93 None
A0A5J4Z1U2 1-139 None
V9EFH5 1-93 None
D0MW69 2-112 None
A0A7S2VI60 29-162 None
W2ZLQ1 1-79 None
A0A2P4X4I6 3-110 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.