DPCstruct | MC47277

Metacluster Properties and Pfam Annotations

Number of structural domains324
Mean domain length (aa)223 ± 41 aa
Standard deviation of domain lengths40.88
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.44
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)13.82
Pfam Score95.02
Assigned Pfam label(s) CL0230- CL0014- CL0056- CL0118

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3QLK4 3-191 None
A0A420CXE5 2-177 None
A0A812U2K1 139-349 None
M7T1Q1 23-260 None
A0A1Y1I3A0 138-448 None
A0A0D0C1H1 41-284 None
A0A849YWW8 320-537 None
A0A1X2FMB1 133-336 None
A0A448FFC0 4-214 None
A0A093VGR6 41-253 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.