DPCstruct | MC47277

Metacluster Properties and Pfam Annotations

Number of structural domains324
Mean domain length (aa)223 ± 41 aa
Standard deviation of domain lengths40.88
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.44
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)13.82
Pfam Score95.02
Assigned Pfam label(s) CL0230- CL0014- CL0056- CL0118

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3F268 2-194 None
D7FK52 97-342 None
A0A672K434 14-241 None
A0A4U0RKF0 7-201 None
A0A812VI07 68-308 None
A3K000 280-484 None
A0A6A6U346 111-373 None
A0A2I0L4W2 2-194 None
M1X2U3 4-175 None
A0A538R8T2 247-470 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.