DPCstruct | MC47227

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)233 ± 18 aa
Standard deviation of domain lengths17.62
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score91.46
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)43.62
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1D6FS76 46-278 SEDRSLHQTPEGSLLDIMRNAHDLLSSCGIDIPMVQDNSEYMHSGPPFLIFLHPALGPFWDIIRQKFVGGSVSKGSELQIEVAEFLW…
F8KVK8 497-754 FDHRLEPKDYHVLKTYLTYHERLKTISVTKHSLCPNGSLAETPEKCFYDLMQNMHALLSQKCHLEMPAMPSEEEYQKQGPSFIALFH…
C1E5I4 150-422 None
A0A4D9BEG4 51-283 None
A0A835EWU2 638-872 None
A0A1F8J2K4 458-662 None
A0A0A9TRM4 1-217 None
A0A835V8U8 3-226 None
A0A2K1YWC0 315-548 None
A0A3D2Q4S6 47-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.