DPCstruct | MC4721

Metacluster Properties and Pfam Annotations

Number of structural domains293
Mean domain length (aa)316 ± 57 aa
Standard deviation of domain lengths57.39
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.57
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)12.25
Pfam Score75.38
Assigned Pfam label(s) PF16026- CL0376- PF04859

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A395IIF6 6-247 None
A0A4S8I7H4 421-635 None
A0A178F434 314-506 None
F1QRV9 70-356 None
A0A2Z6RLX3 618-972 None
A0A2Z6R4J5 324-679 None
A0A2I1F2U1 2-244 None
D4DIS8 5-286 None
Q2GNB3 29-373 None
A0A0D3BN63 1-195 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.