DPCstruct | MC4721

Metacluster Properties and Pfam Annotations

Number of structural domains293
Mean domain length (aa)316 ± 57 aa
Standard deviation of domain lengths57.39
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.57
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)12.25
Pfam Score75.38
Assigned Pfam label(s) PF16026- CL0376- PF04859

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J9HKG2 27-309 AIKSKFLEERQRCLVLEKDLFKSQTEGRRLMQQNKNLQDLNTLNAKNRNNTSSAFTLPSEFKSHWDELVKELILDAFPDFLDRYEEL…
A0A428T2I4 110-449 EKSKKKQEELETNIRDMALSHQRVIDEMTAEHEAEITRRDAEAKSLEERFRAKLRADTTRLQNELTAAHKRMASYSNMDDYVATPDD…
M1WDI8 7-277 None
A0A2K6VIQ4 12-235 None
A0A1M3T3I8 674-1017 None
A0A4S8MXA5 42-376 None
A0A4S2N3C5 277-569 None
A0A167XGU7 150-494 None
A0A7M5V8B5 89-371 None
A0A6G1J160 32-280 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.