DPCstruct | MC47131

Metacluster Properties and Pfam Annotations

Number of structural domains162
Mean domain length (aa)309 ± 57 aa
Standard deviation of domain lengths56.85
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.63
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)16.93
Pfam Score72.46
Assigned Pfam label(s) PF05190- CL0023- PF01624- PF05188- PF05192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A287HL75 20-299 AAGDRSSFVIGLIENRAKEVGVAAFDLRSASLHLSQYIETSCSYQNTKTLLHFYDPNTVIVPPNKTAADGMVGVSELVDKNYQASKK…
A0A6D0EKW8 1-226 LLYAEDFAELALIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLIGFGVENAPRGLCAAGCLLQYVKDTQRTALPHIRSITMERQQ…
A0A162TSG0 45-360 None
A0A2I9CJD1 128-408 None
A0A7R9KIP7 139-412 None
H0EDK5 2-259 None
A0A6S7FWY9 7-415 None
A0A7S3ZRR1 112-413 None
A0A453E8P3 2-223 None
A0A7X7XE34 100-414 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.