DPCstruct | MC47055

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)184 ± 19 aa
Standard deviation of domain lengths18.93
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score76.29
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.50
Pfam Score94.81
Assigned Pfam label(s) PF02671- PF08295- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A8JH38 341-533 YLTKPLSEIVSGDTERVTPSYVKMPPGYPHLVSTGRTPLADSVLNSEFVNVITGSEDYSFKLMRKNQYEESLFRCEDDRYEFEMAIE…
A0A060Z3J4 7-198 SCKRLGSSYRALPKSYTQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATIRALEAV…
M4CWY0 8-192 None
A0A5K4F1Y2 18-211 None
A0A6A2YAD4 44-218 None
A0A6J3CBY4 15-197 None
A0A811MYK2 561-751 None
Q6FNH7 274-471 None
A0A6S8VHN3 212-387 None
A0A0C2MR01 202-385 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.