DPCstruct | MC47049

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)213 ± 22 aa
Standard deviation of domain lengths21.50
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score72.73
Mean fraction of residues predicted as intrinsically disordered0.87
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)30.21
Pfam Score93.75
Assigned Pfam label(s) PF09368- PF04000

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A8J0A8 2-217 TRGMGGAAGGASDRGNALNDLFARQKVSQRYGTDHPSLTARPKGGDEDLPLREPLHERRAKFDAAAARRAARDGAGGFGGDEDDGAE…
A0A161HFD3 376-597 SDYREEDIDEVSIADKLARKKSLRFYTSKIDQQTNKANNGREKFSGDADLPYKERHFERQQRLMEEARKRGLKTSGGAYDPADDFGS…
A0A015JU58 139-388 None
A0A2N9H7K8 243-450 None
A0A7J6R1Q4 1-190 None
A0A811PJL3 249-425 None
A0A7S3CG01 87-349 None
A0A7R9T3T4 276-474 None
A0A4U6VXB2 36-240 None
A0A7S1Z7S1 104-314 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.