DPCstruct | MC470

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)76 ± 9 aa
Standard deviation of domain lengths9.10
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score85.30
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)27.18
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U2YB65 1-64 MEKYTQFSSFDDFLKAGGFFVETQEDFEAIPDEDMDKHVAKTTKFSDWQTMLDTAVSEYALKKL
A0A1M6AEH3 18-93 MSAEKLFNHEFMREHTSFISFEQMIKSSGITMKEIKSISNLESLGSDVFNDFIKNGTKFESWQEMLEKARETMLHK
A0A1C3F6F0 54-126 None
A0A6N2ZUS5 16-87 None
A0A830EMD3 61-142 None
A0A414NVH6 20-92 None
N9CZ16 22-99 None
A0A6N8B412 15-84 None
A0A812FTS6 103-186 None
A0A5N0KT71 9-69 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.