DPCstruct | MC46996

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)249 ± 12 aa
Standard deviation of domain lengths12.13
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score86.87
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)28.87
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R6N2P1 1-226 MTDQVIEDQKHSLDKWIEYFLYDEESKSYEMWEKYWVFQGLQNLGKYDKKTYKFSKRDKTTVYPFPPVEREFIFTTLHLMEDYIKDK…
A0A1Q6TW04 76-319 NKINEARAERLNKWKNFLQEPGAAKGLFDEPVDEELAAKIENNNALKLIVWNAVNSEVKENNRHIPVPFNQKALKETVNYFNDLAPK…
A0A849WSS8 138-390 None
A0A2T2QUR3 86-351 None
A0A4Q6CL32 128-381 None
A0A1F6WHY2 87-335 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.