DPCstruct | MC46985

Metacluster Properties and Pfam Annotations

Number of structural domains102
Mean domain length (aa)207 ± 56 aa
Standard deviation of domain lengths55.50
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score67.79
Mean fraction of residues predicted as intrinsically disordered0.50
Mean length-normalized TM-Score0.31
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)25.10
Pfam Score58.91
Assigned Pfam label(s) PF13867- CL0229- PF12998- CL0318

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B4A619 24-232 NFTLMRDLDNRTEEKKAEIDKLAEEYILNVKNLASEQRVDHLQKIQNAYSKCKEFSDDKVQLAMQTYEMVDKHIRRLDADLARFENE…
E3NBM3 1-176 MDPHYDKLKKDIEKITVVLKRIHVEVPEKIAKEMEKIGELDKRTSEKMAEIEATKVEFIQFYSEMSDADKTSACSYIEKELEIAESW…
A0A077WEZ5 20-182 None
A0A7S3LLV4 48-207 None
A0A813TLD7 6-230 None
A0A2A2KU04 298-436 None
A0A821GKX6 1-137 None
A0A182K2H3 2-232 None
A0A498P408 1-118 None
A0A0C3BIB4 10-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.