DPCstruct | MC46976

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)141 ± 9 aa
Standard deviation of domain lengths9.46
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score87.15
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)31.78
Pfam Score100.00
Assigned Pfam label(s) PF10150

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0J7MXF4 494-635 PQSQTLGISAKIDEEDERRRLRDILSPWLGELPLGYIVRTNAEDQSEEALTFDITYLGKVWRVVQENIVKAKVGERVYEELALPLRS…
A0A2V8GZN0 164-297 VGVSRKIDSREERSRLRGIVREFREQNGFTGGVIIRTAAASRPKEDIVSDLSYFHKVWTEIRQKSESSRAPAVVYREASLVAKLLRD…
A0A803MAT1 310-470 None
A0A1M7TML8 573-712 None
A0A7M3MRU7 129-290 None
A0A2Z5QZS6 168-313 None
A0A1M3LSX8 4-133 None
A0A2S8RE83 136-273 None
A0A819BHT1 634-757 None
A0A022S118 284-432 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.