DPCstruct | MC4695

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)150 ± 36 aa
Standard deviation of domain lengths35.97
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score72.58
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)21.86
Pfam Score60.92
Assigned Pfam label(s) CL0175- PF21373- PF18268

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A139A274 8-141 VCGVCNLEPPKYKCPTCLINYCSLACFKNHKAIGCTKPEPVVPPHSADEPKAGIALEDEDDAALTDEQLRALGTDPAIRALLSSPDL…
A0A0C9W277 1-167 MPPRSRPVCQVCRKDESKYSCSSCRANYCSVACYKEHKVSPPTDAVEDPKPLRPLTSLNWPYVPEESAYPDPLKRDDPKPLQLPQYE…
A0A4Y7NJI5 5-139 None
A0A6P5VVD3 37-181 None
A0A815U434 231-325 None
A0A0M3QVC2 558-696 None
A0A182JGA0 4-139 None
A0A4Y7NG32 111-217 None
A0A1C7NGS9 3-114 None
A0A445AFX2 4-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.