DPCstruct | MC46887

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)190 ± 32 aa
Standard deviation of domain lengths32.31
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score77.20
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.97
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1P8AMW4 2-182 FRVKLLHCFLWDYFSSLPGWDSASSSIHHHISKNLFSLKDAFRAMPLQLFLQVVGSTQKADDIMKKYKQVMRLSELPSEEYKLLMDT…
A0A4U5N1U8 83-309 AIIHEILYHFVYSFDNFEGLPNVYERFPPALSVDEIKAEEVPVYVDADTPTRFMPPLPPFSNAQQGWFMLQDFLNVFPLSVYVLLMP…
A0A3Q0FMD2 33-235 None
A0A821T4P2 851-984 None
A0A1U8PLQ5 279-504 None
A0A820VC16 1-141 None
A0A5B8MTN1 586-788 None
A0A5N4CXN0 435-585 None
A0A821IME6 569-715 None
A0A0E0PRF7 419-622 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.