DPCstruct | MC46833

Metacluster Properties and Pfam Annotations

Number of structural domains212
Mean domain length (aa)120 ± 16 aa
Standard deviation of domain lengths15.86
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.23
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)39.81
Pfam Score84.29
Assigned Pfam label(s) PF04560- PF04997- PF04998- PF04983- PF00623

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4BLE0 79-175 None
A0A2Z4MAX5 186-309 None
A0A059EVX8 3-113 None
A0A2J6KWE3 102-229 None
A0A4U5Q422 334-453 None
A0A5N6NLV6 61-167 None
A0A199YVW5 88-210 None
A0A0B1RYH0 96-234 None
A0A4R0RA16 43-137 None
A0A1S3Y649 3-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.