DPCstruct | MC46833

Metacluster Properties and Pfam Annotations

Number of structural domains212
Mean domain length (aa)120 ± 16 aa
Standard deviation of domain lengths15.86
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.23
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)39.81
Pfam Score84.29
Assigned Pfam label(s) PF04560- PF04997- PF04998- PF04983- PF00623

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G2Y885 75-194 None
A0A1A8H185 610-739 None
A0A5N6L7E2 25-137 None
A0A6P6YB09 379-516 None
A0A6P6Y4J7 130-268 None
A0A2G2ZAF3 4-114 None
A0A7J6I6Q7 102-213 None
A0A7J6T7H2 1-115 None
A0A1Y1WQ63 354-475 None
I6NI52 248-351 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.