DPCstruct | MC46833

Metacluster Properties and Pfam Annotations

Number of structural domains212
Mean domain length (aa)120 ± 16 aa
Standard deviation of domain lengths15.86
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score85.23
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)39.81
Pfam Score84.29
Assigned Pfam label(s) PF04560- PF04997- PF04998- PF04983- PF00623

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K1IR73 111-233 GDYILLKRQPSLQRMSLMAFRARMMPDSCTIRINPCVCPAFNADFDGDEMNIFCASSYPSKAECDVLLAIDKYILSPQNSMPTIYTI…
J9HM71 128-223 EHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEAQAEARVLMLSSNNILSPASGRPITSPTQ…
A0A5S6Q651 428-530 None
A0A1A9X8V1 151-254 None
A0A4Y2UKG3 28-152 None
A0A5D3DCE3 402-539 None
A0A446MYX7 4-125 None
U6KTH3 318-458 None
A0A4U6TSJ4 87-206 None
A0A6D1GKE3 2-111 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.