DPCstruct | MC46781

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)124 ± 11 aa
Standard deviation of domain lengths10.63
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score81.62
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)30.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W6FJM8 4-131 FPRISLRPEVTEYLKNVFLNKEVLAAVGQQEAESRFHKLLICLSHPPSYTCVRASTHLASLEEIRHKLGEELKKQMCSSSAEEFSPQ…
A0A452RIP2 2-111 SVFPKISLRLEVEKYLKEGFMNKEIVSAFGKQAAERKFETLLNHLSHPPSFTTVRVNTHLASVQHVKDLLFDELQKQFNGLNVPILQ…
A0A224Z1S5 25-124 None
A0A7J7ZDE8 2-130 None
A0A453SFC2 6-123 None
A0A7S0YA89 4-134 None
A0A0A9BQZ1 21-164 None
B8BA85 25-140 None
W2MM22 3-122 None
A0A6A4S4M0 415-549 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.