DPCstruct | MC46774

Metacluster Properties and Pfam Annotations

Number of structural domains66
Mean domain length (aa)102 ± 14 aa
Standard deviation of domain lengths13.65
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score82.15
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)49.70
Pfam Score97.17
Assigned Pfam label(s) PF15846- CL0016- PF01158- CL0021

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5J4Z9T3 55-154 WKRGGAGIMTAGQAVGLTKGHIVTKKALVPKVSHRKGALGKRTQFVRSLIREVVGFAPYEKRIIELLRIGKDKRALKFAKKRLGTHL…
G7MYL0 3-103 LRYPMAVGLNKGHKVTKNVSKPRHSRRRGRQSKHTKFVRDMIREVCGFIPYELRAMGLLKVSKEKRALKFIKKRVGTHIRAKRKQEE…
A0A0D3D7K9 36-155 None
A0A0J6YQC8 73-186 None
A0A6D2HSD2 135-245 None
A0A1S3P9C7 22-129 None
L9J9M2 16-99 None
A0A140T8U4 17-117 None
A0A817QYG1 6-132 None
A0A1Q9E7R3 92-212 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.