DPCstruct | MC46772

Metacluster Properties and Pfam Annotations

Number of structural domains73
Mean domain length (aa)131 ± 21 aa
Standard deviation of domain lengths20.98
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score88.35
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)36.74
Pfam Score86.71
Assigned Pfam label(s) PF16201- PF06415- CL0088

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5J4Z1I2 451-567 GTTEFGHVLFDAGRDVPTDLVLINRAVEKNLFASNPAFKAAVEVAKNGGTIHCMGVLSDGLVHSSMKHIEAMLKTLKDSGAASSSIA…
A0A380DP65 1-98 MGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVY…
A0A2V4NWV3 12-134 None
A0A4S8IE37 23-132 None
A0A644SWC1 353-491 None
A0A7V0KIQ0 186-326 None
A0A0C3DYH4 55-176 None
A0A836AUN9 499-672 None
A0A2G9ZM99 89-236 None
A0A4Y7LDF0 78-200 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.