DPCstruct | MC46687

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)400 ± 64 aa
Standard deviation of domain lengths64.32
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score73.98
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)20.48
Pfam Score75.65
Assigned Pfam label(s) PF12145- PF09497

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A317BL80 129-490 KSGAPEVIVPPVYFPGGKPADLFPWTGNNAEDNLTETLVKAGVSNKPQIMNESNTARPSLINNLKNKSGLSTLSTLFVAVLEKRQQT…
A0A183M5C6 69-413 WSFYYNVMLKKYECSNFQDFKKRQTTNIRDTVIPAIDMYKEQVCDWFRELSSNVPLQNLGRRVPFFKDKEEILHELLSNKVPITRAL…
A0A3N4IAZ2 1-395 None
A0A6A4JIS2 150-512 None
Q6C229 1-389 None
J9EUC6 26-458 None
J4IAQ4 29-482 None
A0A183FFU1 15-512 None
A0A0R3RTH2 64-480 None
A0A7R8CKU8 1-299 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.