DPCstruct | MC46677

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)121 ± 12 aa
Standard deviation of domain lengths12.07
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score87.88
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)33.75
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379FIF9 1-137 MKSKHKLGSYEYLCFIHELGHALGLMHINVYLKNIKNDAILTYKYSVMAYQFADIKDADFAGLYPMTFMLVDILLLQYLYGPNMTTR…
A0A365VQJ3 73-180 VKGSYDYLTFVHEIGHALGLKHPFEASSDNSTILTPALDDVRYTVMSYNDSYSYQPTTPMLLDILAIQKLYGANTQYQSGNNFYSWA…
A0A448MKJ9 1-125 None
A0A450YSY6 8-136 None
A0A2E1V7P0 13-111 None
T2IAN2 351-460 None
A0A5E6UZF7 1-138 None
A0A0Q4DED3 114-235 None
A0A7H0GDX0 5-125 None
A0A379Y7N4 53-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.