DPCstruct | MC46674

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)100 ± 10 aa
Standard deviation of domain lengths9.71
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score81.92
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)45.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X2DFX4 1-98 MFFSQHGINRRDFMKLCAALSATMGLSGKAAAQMSQAMTSPERPPVIWIGAQECTGCTESLLRATHPTLENLVLDVIALEYHEVLSS…
P12943 2-83 KFCTAVAVAMGMGPAFAPKVAEALTAKKRPSVVYLHNAECTGCSESLLRTVDPYVDELILDVISMDYHETLMAGAGHAVEEA
A0A101G1K4 1-107 None
A0A4R6A2D8 2-105 None
A0A376UIG1 1-119 None
G1UYL0 2-105 None
A0A2Z6TKL4 5-94 None
A0A847P018 2-100 None
A0A379FVJ8 8-101 None
A0A7G2IUL2 1-106 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.