DPCstruct | MC46673

Metacluster Properties and Pfam Annotations

Number of structural domains3
Mean domain length (aa)65 ± 2 aa
Standard deviation of domain lengths1.89
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score89.26
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.95
Mean intra-cluster sequence similarity (%)65.12
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W1FRJ0 2-67 GNLGLIRATEKFDHSKGYKFSTYATWWIRQAITRAIADKGRTIRIPVHMVEKVNKYHRTHRRMIQT
A0A645DHU7 2-63 IQEGNLGLIRAVEKFDYRRGFKFSTYASWWIKQAITRGLADQGRLIRLPVHFVEKARTVDRL
A0A7R9L7L4 309-374 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.