DPCstruct | MC4666

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)141 ± 10 aa
Standard deviation of domain lengths9.53
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score79.81
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)57.29
Pfam Score100.00
Assigned Pfam label(s) CL0088

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
X0LVS5 159-303 REELFPLQQGSDIHNIILDSYKGRKDGDGVNALLSQLTPVAEKITGKSGCWKRTNGSDLAKVPIPEWNDTTQDGYGGINVIGGFTAA…
X0BMS0 1-146 MESMREELFPIQQGTDIHRFIMDSHEKSLRDEVNARVSRMTPSAEKITGKPGTYKSENGSTYDPPAKPEWNDKTKPGFGGINVIGGL…
A0A2H3U004 101-226 None
A0A1B8A8G9 779-925 None
A0A420M8V4 200-348 None
A0A0S6XG16 360-484 None
A0A4E9EIL4 376-525 None
X0B816 382-516 None
A0A2H3G828 1-150 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.