DPCstruct | MC46658

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)124 ± 21 aa
Standard deviation of domain lengths20.97
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.35
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.37
Pfam Score92.86
Assigned Pfam label(s) CL0023- CL0167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A136K0H3 141-255 ELIDMRDVFKREGKDVGLSQELLDAISQAAQRGEQMIVLMNRRGFSQFVLCRSCGEMLKCKNCDITLTFHRREARLTCHYCGYGEPA…
A0A6I2IZT5 24-127 LPSMKLVDTRRLQMKHGMSPQLLEAIGERLANKEQSLIFLNRRGFAPVLHCQSCGWVSNCPRCTAFTVLHRAGRGHRLQCHHCGYQA…
A0A7V6KW68 402-521 None
A0A7V9EYB3 67-182 None
T0THK9 1-92 None
G6EPK4 86-199 None
A0A0G1HHS4 322-464 None
V9G3X6 295-421 None
A0A098TM32 165-275 None
A0A7V4S5M1 17-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.