DPCstruct | MC46647

Metacluster Properties and Pfam Annotations

Number of structural domains205
Mean domain length (aa)146 ± 23 aa
Standard deviation of domain lengths22.66
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score70.62
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)30.43
Pfam Score99.30
Assigned Pfam label(s) PF06212- PF03134- CL0040

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2LHA4 546-710 MGASLSRCLCLGVGVAYPAYASFKALERPESGHGEKQWLTYWVVYGASTSVESVASPLLCLVPGYNITKTLFLIWMMSPQTKGATIV…
A0A183UYW1 225-346 QLAYVVVGFLSLYLIIGECAQLVCNLIGFAYPAYASVKAIRTVEKDDDTQWLTYWTVFAFFSLLDFFAHVIMDVVPLYWLAKVIFLL…
A0A397IRU6 1-114 None
A0A5N6PHN2 124-280 None
A0A0M3IQN6 3-116 None
A0A6P6FVL5 1-113 None
A0A0B7N740 652-754 None
A0A182KFL1 247-386 None
Q66IF1 49-192 None
D0N334 191-301 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.