DPCstruct | MC46638

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)124 ± 10 aa
Standard deviation of domain lengths10.15
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score72.03
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)43.69
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R1D6B2 1-122 MPPRKKAGASSQFDASEVMQPVQALRGRMDAAGSSRKRTLEEVGVSGVSKEVQHMGAEDVSAEIEALCMRAVASIMRGDGFSYMMPS…
A0A445BGL5 4-130 SSKKRRRTNTDDLPFKNKLKLDSTILQILKDFSTSSSSSSSSSSSKTLTLQDLSLPFSCREVSDLSLSSVQSNIESLVLRIAHSILS…
A0A7J7KWY5 10-132 None
A0A0L9T9E8 358-480 None
A0A498K7L3 375-495 None
A0A4D8ZZR8 92-221 None
A0A7S3A1Z0 48-189 None
A0A2I0IUW9 18-120 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.